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Yosuke Kokunai Selected Research

Hyperkalemic Periodic Paralysis

11/2018A204E mutation in Nav1.4 DIS3 exerts gain- and loss-of-function effects that lead to periodic paralysis combining hyper- with hypo-kalaemic signs.
6/2012A sodium channel myotonia due to a novel SCN4A mutation accompanied by acquired autoimmune myasthenia gravis.

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Yosuke Kokunai Research Topics

Disease

4Myotonia
10/2016 - 07/2011
3Paralysis (Palsy)
01/2020 - 07/2011
2Hyperkalemic Periodic Paralysis
11/2018 - 06/2012
2Hypokalemic Periodic Paralysis (Periodic Paralysis, Hypokalemic)
11/2018 - 10/2011
2Myotonic Dystrophy (Dystrophia Myotonica)
04/2016 - 06/2011
1Andersen Syndrome
03/2014
1Myotonia Congenita (Thomsen Disease)
01/2013
1Potassium aggravated myotonia
06/2012
1Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital)
06/2012
1Myotonic Disorders (Paramyotonia Congenita)
06/2012
1Muscular Dystrophies (Muscular Dystrophy)
06/2011
1Infections
03/2011
1Encephalitis (Encephalitis, Rasmussen)
03/2011
1Virus Diseases (Viral Diseases)
03/2011
1Glycogen Storage Disease Type II (Pompe's Disease)
03/2010

Drug/Important Bio-Agent (IBA)

3Sodium Channels (Sodium Channel)IBA
10/2016 - 07/2011
2Calcium Channels (Calcium Channel)IBA
11/2018 - 10/2011
2Voltage-Gated Sodium ChannelsIBA
11/2018 - 06/2012
2Proteins (Proteins, Gene)FDA Link
04/2016 - 03/2011
1Lysine (L-Lysine)FDA Link
01/2020
1Arginine (L-Arginine)FDA Link
01/2020
1ChloridesIBA
10/2016
1Inwardly Rectifying Potassium Channels (Inward Rectifier Potassium Channels)IBA
03/2014
1Chloride Channels (Chloride Channel)IBA
01/2013
1PotassiumIBA
10/2011
1RNA (Ribonucleic Acid)IBA
06/2011
1AntibodiesIBA
03/2011
1Glutamic Acid (Glutamate)FDA Link
03/2011

Therapy/Procedure

1Enzyme Replacement Therapy
03/2010